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Satish PillaiSatish Pillai, PhD

Current Positions:

  • Associate Investigator, BSRI
  • Assistant Adjunct Professor, UCSF Department of Medicine, Division of Infectious Diseases

Contact Information:
270 Masonic Ave.
San Francisco, CA 94118
Phone: (415) 513-4461
Fax: (415) 567-5899
Email: spillai@bloodsystems.org

 

 

Download a scientific summary [pdf file]

Download a curriculum vitae [pdf file]

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Education:

  • B.S., Ecology & Evolutionary Biology, University of Arizona
  • Ph.D, Evolutionary Biology, University of California, San Diego

Training / Appointments:

  • Graduate Research Assistant, HIV Sequence Database, Los Alamos National Laboratory
  • Postdoctoral Teaching Fellow, UCSF Department of Medicine
  • Research Associate, Center for Comparative Genomics, California Academy of Sciences
  • UCSF AIDS Research Institute (ARI) Executive Committee Member

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Research Interests:

  • Molecular Evolution
  • Viral Pathogenesis

Current Research:

  • Viral genetic determinanats of HIV/AIDS pathogenesis and transmission
  • Molecular evolution of HIV-1 in the central nervous system
  • Effects of interferon-induced host restriction factors on retroviral replication
  • Effects of host genetic variation on the HIV-1 latent reservoir
  • Estimation of HIV-1 incidence based on viral diversity

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Recent Publications:

Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene W, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Gunthard H, Wong JK. Role of retroviral restriction factors in the interferon-?-mediated suppression of HIV-1 in vivo. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3035-3040. PMCID: PMC3286922.

Jha AR, Nixon DF, Rosenberg MG, Martin JN, Deeks SG, Hudson RR, Garrison KE, Pillai SK. Human endogenous retrovirus K106 (HERV-K106) was infectious after the emergence of anatomically modern humans. PLoS One. 2011;6(5):e20234. PMCID: PMC3102101.

Skasko M, Tokarev A, Chen CC, Fischer WB, Pillai SK, Guatelli J. BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: Evidence for a post-ER mechanism of Vpu-action. Virology. 2011 Mar 1;411(1):65-77. PMCID: PMC3086044.

Rempel H, Sun B, Calosing C, Pillai SK, Pulliam L. Interferon-? drives monocyte gene expression in chronic unsuppressed HIV-1 infection. AIDS. 2010 Jun 19;24(10):1415-23. PMCID: PMC2991092.

Wong JK, Strain MC, Porrata R, Reay E, Sankaran-Walters S, Ignacio CC, Russell T, Pillai SK, Looney DJ, Dandekar S. In vivo CD8+ T-cell suppression of SIV viremia is not mediated by CTL clearance of productively infected cells. PLoS Pathog. 2010 Jan 29;6(1):e1000748. PMCID: PMC2813272.

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