Sheila Keating, Ph.D.

Current Positions:

• Staff Scientist II - Immunology Core, BSRI

Contact Information:
270 Masonic Ave.
San Francisco, CA 94118
Phone: (415) 749-6606 x499
Fax: (415) 775-3859
Email: skeating@bloodsystems.org

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Download a curriculum vitae [pdf file]

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Education:

• Weatherall Institute of Molecular Medicine, Open University, Centre for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
  PhD Research Supervisor: Professor Adrian Hill
• Tulane School of Public Health and Tropical Medicine, New Orleans, LA
  MSPH in Tropical Medicine
• College of the Holy Cross, Worcester, MA
  BA in Biology

Training/Appointments:

• Postdoctoral Research Fellow, B cell Memory and Pneumococcal Vaccines, Department of Infectious Diseases and Microbiology, Institute of Child Health, University College London, London, UK
• Scientist, Malaria Vaccine Program, Centre for Clinical Vaccinology and Tropical Medicine Nuffield Department of Medicine, University of Oxford, Oxford, UK
• Senior Research Program Coordinator, Core Immunology Laboratory, HIV Prevention Trials Network, Division of Infectious Diseases, Johns Hopkins University, School of Medicine, Baltimore, MD

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Research Interests

• Development of new assays for the detection of HIV incidence
• Investigation of immune responses during early infection
• Study of the maturation of B and T cell responses over time in response to vaccination or infection

Publications

S. J. Dunachie, M. Walther, J. E. Epstein, S. Keating, T. Berthoud, L. Andrews, R. F. Andersen, P. Bejon, N. Goonetilleke, I. Poulton, D. P. Webster, G. Butcher, K. Watkins, R. E. Sinden, G. L. Levine, T. L. Richie, J. Schneider, D. Kaslow, S. C. Gilbert, D. J. Carucci, and A. V. S. Hill. 2006. A DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccine Encoding Thrombospondin-Related Adhesion Protein but Not Circumsporozoite Protein Partially Protects Healthy Malaria-Naive Adults against Plasmodium falciparum Sporozoite Challenge. Infection and Immunity. 74(10):5933-42.

Bejon P., S. Keating, J. Mwacharo, O.K.Kai, S. Dunachie, M. Walther, T. Berthoud, T. Lang, J. Epstein, D. Carucci, P. Morris, J. Cohen, S.C.Gilbert, N. Peshu, K. Marsh, A.V.Hill. 2006. Early IFN gamma and IL 2 responses to vaccination predict the late resting memory in malaria naive and malaria exposed individuals.  Infect Immun. Nov;74(11):6331-8.

Keating, S.M., P. Bejon, T. Berthoud, J. Vuola, S. Todryk, D. P. Webster, V.S. Moorthy, S.J. McConkey, S.C. Gilbert , A.V.S. Hill. 2005. Durable Human Memory T Cells Quantifiable by Cultured ELISPOT Assays are Induced by Heterologous Prime Boost Immunization and Correlate with Protection against Malaria. J. Immunol, 175(9):5675-80.

Vuola, J. M., S. Keating, D. P. Webster, T. Berthoud, S. Dunachie, S. C. Gilbert, and A. V. Hill. 2005. Differential immunogenicity of various heterologous prime-boost vaccine regimens using DNA and viral vectors in healthy volunteers. J Immunol 174:449.

Keating  S.M., R. C. Bollinger, T. C. Quinn, J. B. Jackson, and L. M. Carruth. 2002. Cross-clade T Lymphocyte Mediated Immunity to HIV-1. Implications for Vaccine Design and Immunodetection Assays. AIDS Res Hum Retroviruses. 18(14):1067-79.

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