Mark Seielstad, PhD
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For the last decade, Mark Seielstad, Ph.D., has been at the forefront of research in human and medical genetics and genetic epidemiology. While a postdoctoral fellow and, later, a faculty member at the Harvard School of Public Health, Dr. Seielstad accomplished a transition from the anthropological and evolutionary genetics of his doctoral training to the related field of medical genetics and genetic epidemiology. This led to a nearly 8 year stint at the Genome Institute of Singapore, where he rose to become the Senior Group Leader and Associate Director of Human Genetics. While there, he built and ran a high-throughput genomics and computational lab centered on the genome-wide genotyping and analysis of SNP variation as it relates to common, primarily immune-related diseases of importance to public health. Now at BSRI in San Francisco, Dr. Seielstad continues his search for human genetic variation that alters susceptibility to and outcomes of infections caused by pathogens of importance to the blood supply. Additional efforts aim to gain insight into the genetic causes of pregnancy and transfusion related alloimmunization. A third research initiative seeks to address a wide variety of other genetic questions of health and disease that are inherently answerable in large cohorts of blood donors and recipients.